Organic Acids
Medchemexpress LLC (S)-2-hydroxypropanoic acid | 79-33-4 | MFCD00064266 | 99.6% | 90.08 g/mol | C3H6O3 | 500mg
L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid L-Lactic acid has antiproliferative activity[1][2][3]
Medchemexpress LLC Lactic acid (potassium) | 996-31-6 | 60.8% | 50 G
Lactic acid (potassium) | 996-31-6 | 60.8% | 50 G
Medchemexpress LLC Lactic acid sodium | 72-17-3 | 98.0% | 10 ML
Lactic acid sodium | 72-17-3 | 98.0% | 10 ML
eMolecules 65-85-0 | Benzoic acid | Chem-Impex | MFCD00002398 | 122.123 | C7H6O2 | 99.000 | OC(=O)c1ccccc1 | 1kg | 490847745
Benzoic acid | Chem-Impex | 65-85-0 | MFCD00002398 | 122.123 | C7H6O2 | 99.000 | OC(=O)c1ccccc1 | 1kg | 490847745
Medchemexpress LLC Valerenic acid | 3569-10-6 | MFCD00075694 | 99.0% | 234.33 | C15H22O2 | 1 MG
Valerenic acid is a sesquiterpenoid research compound that acts as a positive allosteric modulator of GABAA receptors and shows activity at 5-HT receptors. It is provided in small, laboratory quantities for pharmacological and biochemical studies, commonly used in anxiolytic and antioxidant research.
- Acts as a positive allosteric modulator of GABAA receptors.
- Partial agonist activity at 5-HT receptor subtypes.
- High purity for research use (99.0%).
- Supplied in small, laboratory-friendly quantities ideal for assay development.
- Suitable for receptor pharmacology, binding studies, and antioxidant assays.
Medchemexpress LLC Norleual TFA | 99.9% | 888.97 | 1 MG
Norleual TFA is an angiotensin (Ang) IV analog and a hepatocyte growth factor (HGF)/c-Met inhibitor with an IC50 of 3 pM. It acts as an AT4 receptor antagonist and demonstrates potent antiangiogenic activities. It significantly reduces HGF-dependent c-Met and Gab1 phosphorylation and attenuates HGF-dependent c-Met activation and downstream signaling. In vivo, Norleual TFA suppresses pulmonary colonization by B16-F10 murine melanoma cells.
- Reduces HGF-dependent c-Met and Gab1 phosphorylation
- Attenuates HGF-dependent c-Met activation and downstream signaling
- Inhibits HGF-dependent signaling, proliferation, migration, and invasion in multiple cell types
- Suppresses pulmonary colonization by B16-F10 murine melanoma cells
Medchemexpress LLC Mi-1061 Tfa | 1410737-35-7 | 97.5% | 696.47 | C32H27Cl2F4N3O6 | 25MG
MI-1061 TFA is the trifluoroacetate (TFA) salt of MI-1061, a potent, orally bioavailable inhibitor of the MDM2-p53 protein-protein interaction. It activates p53, induces apoptosis in tumor models, and shows selective activity in p53 wild-type cell lines.
- Potent biochemical MDM2-p53 interaction inhibitor (IC50 = 4.4 nM; Ki = 0.16 nM).
- Selective cellular activity with IC50 = 100 nM in SJSA-1 and 250 nM in HCT-116 p53+/+; >10,000 nM in p53-/- cells.
- Trifluoroacetate salt presented as a solid form.
- Molecular weight 696.47 and molecular formula C32H27Cl2F4N3O6.
- Intended for research use as a tool compound to study p53 activation and antitumor effects.
- Purity listed as 97.47%.
Medchemexpress LLC SJ1008030 TFA | 2863634-97-1 | 99.8% | 987.96 | 5 MG
SJ1008030 TFA is a JAK2 PROTAC that selectively degrades JAK2. It inhibits MHH-CALL-4 cell growth with an IC50 of 5.4 nM and can be utilized for leukemia research. The compound is composed of a JAK2 ligand, a Cereblon ligand, and a linker.
- Selective JAK2 PROTAC degrader.
- Inhibits MHH-CALL-4 cell growth with an IC50 of 5.4 nM.
- Can be used for leukemia research.
- Degrades JAKs, GSPT1, and IKZF1 in a dose-dependent manner in MHH-CALL-4 cells.
- Dose-dependently degrades JAK2 and GSPT1 protein in xenograft bone marrow SJBALL021415 cells, indicating inhibition of the JAK-STAT signaling pathway.
Medchemexpress LLC Cpn-267 tfa | 1279.27 | 1 MG
Cpn-267 tfa is a selective agonist for neuromedin U receptor 1 (NMUR1) with an EC50 of 0.25 nM. This compound has been shown to suppress body weight gain in mice, suggesting its potential use in the study of obesity. It is provided as a solid for research applications.
- Selective NMUR1 agonist.
- Potent activity at nanomolar concentrations.
- Demonstrated suppression of body weight gain in animal models.
- Suitable for obesity research.
Medchemexpress LLC 7-TFA-ap-7-Deaza-dA | 178420-75-2 | 98.8% | 399.32 | 1 ML
7-TFA-ap-7-Deaza-dA is a modified nucleoside that can be used in the synthesis of deoxyribonucleic acid or nucleic acid. It functions as a click chemistry reagent, containing an alkyne group that undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Modified nucleoside.
- Can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
- Functions as a click chemistry reagent.
- Contains an alkyne group for reactions.
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups.
Medchemexpress LLC LL-37 amide TFA | 99.3% | 4492.28 | 10 MG
LL-37 amide TFA is a selective agonist of formyl peptide receptor-like FPRL1, effective in inhibiting periodontal pathogens. It functions by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. This modified form of LL-37 also regulates inflammatory responses, promotes angiogenesis, and shows improved stability and enhanced resistance to enzymatic degradation compared to natural LL-37.
- Effective against periodontal pathogens
- Activates FPRL1-mediated immune cell chemotaxis
- Disrupts bacterial cell membrane integrity
- Regulates inflammatory responses and promotes angiogenesis
- Improved stability and resistance to enzymatic degradation
- Good antibacterial effects against Gram-positive and Gram-negative bacteria
- Used in research for infection-related diseases and wound healing